• Francisella noatunensis ssp. noatunensis in Atlantic cod - Intracellular localization, innate immune responses and antibacterial proteins 

      Bakkemo, Kathrine Ryvold (Doctoral thesis; Doktorgradsavhandling, 2016-11-24)
      SUMMARY Francisellosis has in the cod farming industry caused big economic losses because of no available vaccine or treatments. Understanding host-pathogen mechanisms is especially important when traditional vaccine strategies using inactivated bacteria are not functional. The focus of this thesis has been to study interactions between the host and the pathogen causing the disease. The bacterium ...
    • Multiple specialised goose-type lysozymes potentially compensate for an exceptional lack of chickentype lysozymes in Atlantic cod 

      Seppola, Marit; Bakkemo, Kathrine Ryvold; Mikkelsen, Helene V.; Myrnes, Bjørnar; Helland, Ronny; Irwin, David; Nilsen, Inge Waller (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-21)
      Previous analyses of the Atlantic cod genome showed unique combinations of lacking and expanded number of genes for the immune system. The present study examined lysozyme activity, lysozyme gene distribution and expression in cod. Enzymatic assays employing specific bacterial lysozyme inhibitors provided evidence for presence of g-Type, but unexpectedly not for c-Type lysozyme activity. Database ...